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glutathione oxidation mechanism Tumor-targeted catalysis with ruthenium nanoreactors against hypoxic osteosarcoma Frontiers | Glutathione: A Samsonian
Description
In summary, the co-delivery system integrating CUR and miR155 (CUR/miR155@DssD-Hb NPs) demonstrates promise as a promising strategy for the immunotherapy of melanoma and triple negative breast cancer

In addition, 47 genes were downregulated in the recombinant strain at all three time points, including the hsp1 heat shock protein-coding gene, the trxA1 thioredoxin-coding gene, and the dinP, mutY, umuC, and uvrB DNA damage repair-related protein-coding genes, potentially indicating that the recombinant strain was less susceptible to stress and had less DNA damage than the control strain in acid stress conditions

Hence, the importance of therapeutic measures to reduce oxidative damage and enhance DNA repair is emphasized

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