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Removal of the terminal residue of the type A antigen -N-acetylgalactosaminidase produced by Clostridium perfringens has been used to convert type A red cells 34 , but the antigens cannot be completely eliminated

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At the same time, it can be observed that the difference in cytotoxicity during the process of increasing DOX concentration is getting smaller and smaller, indicating that the effect of chemotherapeutic drugs begins to play a leading role as the concentration of doxorubicin increases

Because lipomidase alone could free most lipoic acid from Kgd2, this increase indicates that the release of lipoic acid with trypsin and lipoamidase treatment was very efficient