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In 2024, Demir-Dora et al

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Quantitative determination of uric acid in insect feces by lithium carbonate extraction and the enzymatic-spectrophotometric method

However, under oxidative stress, oxidative modification of cysteine residues in Keap1 causes conformational changes that weaken its binding to Nrf2, allowing Nrf2 to dissociate from Keap-1 and rapidly translocate to the nucleus