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48,49 This GSH depletion impairs the capacity of GPx4 to reduce lipid hydroperoxides and to interrupt the propagation of LPO
This mixture is then combined with an aqueous buffer, leading to the spontaneous formation of SUVs [39]
Cell lines such as HT-1080 fibrosarcoma cells and Panc-1 pancreatic cancer cells have robust ferroptotic responses and are frequently used as model systems to study ferroptosis mechanisms
