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Description
Zavegepant exhibited potent inhibition (K i = 23 pM) of CGRP binding to human CGRP receptor expressed in cell membranes and demonstrated potent and full reversal of CGRP-induced dilation of ex vivo human intracranial arteries (EC 50 =880 pM)
NAC was administered orally with 150 mL of still mineral water
A.BaileyG
Experimental dry eye stimulates production of inflammatory cytokines and MMP-9 and activates MAPK signaling pathways on the ocular surface
