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Another example is a study that reported Curcumin Encapsulated Lipidic Nanoconstructs (CLEN) achieving an approximately 1.4-million-fold increase in aqueous solubility and about a 70-fold improvement in oral bioavailability compared to free curcumin ( In summary, these early studies collectively demonstrated that liposomal encapsulation could extend the shelf-life of labile nutrients and modestly enhance their bioavailability relative to non-encapsulated forms
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