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2010 Sep;24(9):3580-9
Caspase-8 serves as a critical molecular switch within this network: its activation preferentially drives apoptosis while suppressing RIPK3MLKLmediated necroptosis, whereas functional inhibition or depletion of caspase-8 permits necroptosis or PANoptosis to become dominant
Ahmad I, Akhtar MJ, Zahir ZA, Naveed M, Mitter B, Sessitsch A
NOX4 is highly expressed in neurons but it is activated by different mechanisms compared to NOX1 and NOX2 (Hordijk, 2006)
