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Semaglutide participants regained about two-thirds of their lost weight at 52 weeks, and a tirzepatide withdrawal trial also measured substantial regain

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In conclusion, MQC is an integrated network that monitors mitochondrial quality and works in concert to maintain mitochondrial homeostasis by coordinating various processes, including mitochondrial biogenesis, mitochondrial autophagic degradation, and the balance of mitochondrial dynamics (fission, fusion) (Zhou et al., 2023)

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