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Over-loss and muscle pooled SURMOUNT, BMI below 22 reached by about 7% (as early as week 12), toward about 15% by week 88 in the longest trial, clinical underweight under 0.4% (Almandoz 2026)

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This is because if the trigger is taken too late, the eggs may not be available or mature enough at the time of egg retrieval

Testing includes quantitative assay verification, heavy metals screening, and comprehensive microbial analysis