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Description
10.1074/jbc.M306914200 46 MannuF.AreseP.CappelliniM

at Erasmus University Medical Center in the Netherlands, the peptide is based on the FOXO4 domain that binds p53, but synthesized with D-amino acids in reverse order to create a protease-resistant mirror image that retains binding activity

M.QiangJ.AshbridgeE.MingerJ.YearoutD.HornS.et al

In the presence of guide RNA (gRNA) and Cas9 endonuclease, the gRNA directs the Cas9 endonucleases to cleave the DNA at a specific location, creating indels in the gene, inducing a frameshift mutation, generating a constitutive knockout
