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TrkB signaling undergoes transactivation, which involves several GPCRs (G-protein-coupled receptors), such as A 2A adenosine receptors 32 , PACAP (pituitary adenylate cyclase-activating polypeptide) receptors PACR1 48 , dopamine D 1 receptors 49 , cannabinoid receptors CB 1 R 50

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MET mutation associated with responsiveness to crizotinib

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Aging Cell 20 , e13329 (2021)

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GI side effects (nausea, vomiting) are titration-dependent

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