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1,2,6 Skin hyperpigmentation, glossitis, and infertility have also been reported

6080% adenosylcobalamin) with total stores reaching up to 5 mg (ref1)

The following criteria were considered: Full economic evaluations: cost-utility analysis, cost-effectiveness analysis, cost-benefit analysis Economic evaluations reporting incremental cost-effectiveness ratios (i.e., cost per quality-adjusted life year/life years gained or cost per event avoided) Studies in patients with confirmed vitamin B12 deficiency Studies in English Abstracts were reviewed by a single reviewer and, for those studies meeting the eligibility criteria, full-text articles were obtained

They might also apply pressure to the suspected muscle knot to see if it causes referred pain (pain in another area of the body)