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Description
Vitamin B12 deficiency is Some people with Crohns disease may undergo surgical removal of part or all of the ileum, making it difficult to absorb vitamin B12

High concentrations of reducing agents such as dithiothreitol (DTT) can reduce the immobilized metal ion and should be avoided

Thus, there is a recommendation utilizing approaches other than this one

Depending on the patient's skin characteristics and needs, these treatments can be delivered as monotherapy or combined
