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Description
Paradoxical repigmentation of graying hair has been associated with anti-PD-1/PD-L1, probably through re-immune stimulation of melanocytes [56]

6 (June 9, 2018): e2775
Also, metabolites of VPA -oxidation (including propionic derivatives and 4-en-VPA) inhibit the mitochondrial CPS I, which is the first enzyme necessary for ammonia elimination via the urea cycle in the liver [19, 24]

Heart-specific SCOT knockout mice (in which terminal oxidation of -hydroxybutyrate is prevented) exhibit increased fatty acid oxidation (Schugar et al., 2014), revealing the interrelated characteristics of myocardial ketone oxidation and fatty acid oxidation
