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Additionally, ATG12 can support apoptosis via direct inhibition of Bcl-2 and Mcl-1 [307]

1, the association of genetically predicted l-carnitine with CAD was consistent in different data sources (CARDIoGRAMplusC4D, the UK Biobank and FinnGen)

In contrast, rapid-acting agents such as ketamine induce acute mitochondrial metabolic reprogramming and mitophagy engagement, highlighting that early correction of bioenergetic and redox disturbances may suffice to trigger downstream synaptic and behavioral recovery