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These pre-clinical studies attributed the recovery in symptom profile to modulation of glucose transport, over-expression of mitochondrial genes, bypassing defective pathways of ETC (electron transport chain), and improvement in mitochondrial biosynthesis, modulation of microbiota, regulation of brain neuronal networks, and promoting synthesis of white matter in the brain [168]

Its a very limited study and I dont know how accurate it was, I assume that the b12 wasnt the little vials that we use today hence the smaller amounts injected in the study