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The synergy between elevated glucose levels and free radicals triggers the formation of advanced glycation products (AGEs) and the stimulation of their receptors (RAGE)

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(v) Finding genetic susceptibilities to metal toxicants, such as by using Drosophila models (178), could uncover predispositions to toxicant-induced neurological diseases and could aid in preventative measures by avoiding toxicant exposures

10.3389/fphar.2024.1434812 7 AydinS
