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Among the NK cells subset, CD56 dim PC-phospholipase C bright cells are associated with cytotoxic function, whereas CD56 bright PC-phospholipase C low/- cells exhibit immunoregulatory properties (133) ( Figure 3 )

Concretely, VD supplementation in MASLD patients resulted in significant improvements in metabolic profiles and inflammation by upregulating levels of lipid profiles (HDL-C) and downregulating levels of liver enzymes (ALT and AST), LDL-C, and reducing pro-inflammatory microRNAs (MiR-21 and MiR-122) [81]

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a Qualitative Study Ji-Hye Jung, Young-Gyu Cho, Da-Ye Ji, Jae-Heon Kang Korean Journal of Health Promotion.2016