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doi: 10.1200/JCO.2003.05.139
How the four axes of cellular iron regulation described (IRE-IRP, PHD-HIF, KDM3B-mTOR-TTP, and haem-HRI) act in concert, and in different cell types across different anatomical sites and tissues where local concentrations of iron may fluctuate substantially, is unknown
However, recent research challenges this notion, revealing the presence of microorganisms within venom and its secreting glands
Consequently, the researchers concluded that the pharmacological activation of SOD3 within the pulmonary system might serve as a therapeutic intervention for managing COPD and emphysema [24]
