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Description
PMID 9183545

MR is strongly recommended as a means of prioritizing drug targets for cardiovascular research, to avoid expensive failures in phase III randomized controlled trials (RCTs) [18, 19] and to identify mechanistic targets of intervention, complementary to RCTs [19]

Hoek et al, 2008

We recently found that ccz-1(-) mutants lack gut granules, whereas rab-7(-) mutants have only a minor defect in gut granule protein localization, and sand-1 is dispensable for gut granule biogenesis [19]
