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The Wnt signalling pathway presents another avenue for synergistic interaction, where T4 influences -catenin nuclear translocation and Wnt target gene expression [67], while Selenium affects Wnt/-catenin signalling through regulation of oxidative stress [133]
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In 2021, FDA accelerated the approval of Tepotinib for marketing to treat adult patients with metastatic non-small cell lung cancer with MET exon 14 (MET ex14) jump mutation [8, 16]
