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We also lack the ordinary pharmacological basics a clinician would want before recommending anything: well-characterised human pharmacokinetics, dose-response and safety ceilings, interaction data with common medications, and any signal about effects in people with pre-existing cancer risk the population for whom a telomerase-activating compound is most theoretically concerning
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PGC-1 is the master regulator of mitochondrial biogenesis [18], and ALA helps AMPK respond better to PGC-1
