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SAR studies have revealed key functional groups, such as thiols, phenolic hydroxyls, and quinone moieties, which increase the free radical scavenging activity and neuroprotective properties of these compounds

Stovell MG, Helmy A, Thelin EP, Jalloh I, Hutchinson PJ, Carpenter KLH

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In contrast, alternatively activated macrophages, or M2, are induced in response to anti-inflammatory cytokines such as IL-4 or IL-13 (Fig
