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Semaglutide animal studies have shown an increased risk of medullary thyroid carcinoma
One of the first requirements is a clear scientific rationale explaining why the compound's mechanism of action or biological target may potentially provide a therapeutic benefit
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The inhibition of HDAC1 expression increases the expression of DUSP1, significantly reduces fibrosis markers, and hinders the phosphorylation of Smad3, thus alleviating UUO-induced renal tubules injury and renal fibrosis (Wang S
