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Notably, most clinical investigations studied women (1404 female versus 83 male participants), which is expected since estrogen declines after age 30 years, and further estrogen decline with aging represents health challenges, as well as a reduction in QOL [9, 10, 19,20,21,22] and a degradation in the most visible organ of the bodythe skin [9, 10]

[DOI] [PMC free article] [PubMed] [Google Scholar] 202.Reddy N.V.L.S., Raju M.G., Papani J., Keerthana E

Foudah AI, Alam P, Shakeel F, Alam A, Salkini MA, Alshehri S (2022) A simple, cost-effective, and green HPTLC method for the estimation of ascorbic acid in solvent and ultrasound-assisted extracts of Phyllanthus emblica , Capsicum annuum , and Psidium guajava