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Although selenium supplementation demonstrates potential benefits in reducing autoantibody levels, the existing body of researchprimarily limited to short-term observations of 36 monthsfails to establish a definitive causal relationship between decreased antibody titers and sustained functional improvements in the neurological system (44, 264)

By promoting osteoblast activity and possibly balancing the bone remodeling process, MOTS-c could emerge as a novel target for addressing osteoporosis or age-related bone fragility (pending further research)

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