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doi: 10.1093/annonc/mdh006 14 RehmanSKHaynesJCollignonEBrownKRWangYNixonAMLet al
In an AD mouse model (APP NLGF ), increased expression of NRF2 reduced inflammation and oxidative stress and improved cognition (Uruno et al., 2020)
Over time, what should be an acute injury becomes a chronic degenerative condition, sometimes called plantar fasciosis to reflect the lack of active inflammation
And phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) and mitogen-activated protein kinase (MAPK) signal transduction pathways are also likely to regulate FASN expression (63, 64)
