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However, you must start slowly with a low concentration of tretinoin, perhaps only once or twice a week

Inflammation Res Off J Eur Histamine Res Soc (2020) 69:110310

Studies have shown that cancer itself can cause effector T (Teff) cell metabolism disorders, and there is a negative correlation between the degree of glycolytic activity of cancer cells and the antitumor function of infiltrating T cells (282)

Nature 478:264268 Acknowledgments We thank Conselho Nacional de Desenvolvimento Cientfico e Tecnolgico (CNPq, Grant 473090/2011-2) and Spanish Ministry of Science and Innovation (Grant BFU2010-15090) for financial support