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In this study, Hmox1 upregulation occurs only at the very first phases of neurodegeneration (3 hours after rotenone challenging, a time which represents the pre-diagnosis stage in human PD based on dopaminergic neuron loss)

in particular, they employed a Tetrahedral framework nucleic acid-VitB12 complex (TVC), which was aimed at overcoming possible limitations due to the bloodbrain barrier and TC availability, obtaining good results on disease symptoms [137]

Global Initiative for Chronic Obstructive Lung Disease (2023)

Structural understanding of the recycling of oxidized ascorbate by dehydroascorbate reductase (OsDHAR) from Oryza sativa L
