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This condition can occur for a number of reasons, including a high fat diet, metabolic disorders, or the use of certain medications

Structure 20:21612173 Chen VB, Arendall WB, Headd JJ, Keedy DA, Immormino RM, Kapral GJ, Murray LW, Richardson JS, Richardson DC (2009) MolProbity: all-atom structure validation for macromolecular crystallography

This dysfunction leads to increased intraocular pressure (IOP), causing mechanical stress and eventual death of RGCs ( Figure 2 The global prevalence of glaucoma among individuals aged 40 to 80 years is estimated at 3.54% ( Each type of glaucoma necessitates tailored treatment strategies focused on reducing IOP

This observation suggests that this ratio may be of considerable importance in the assessment of CHD risk (56)