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More or less frequent injections can lead to overdose or underdose
Another aspect driving future clinical translation of gene editing of immune cells is their amenability to genetic manipulation
We are also very grateful to Dr Sokol (Indiana University) for providing most of the let-7 related fly lines and fragments (17)-luc vectors and thank Dr Rosbash (Brandeis University), Rouyer (Institut de Neurobiologie Alfred Fessard), Ceriani (Fundacin Instituto Leloir and Instituto de Investigaciones), Johnston (Columbia University) and Hardin (Texas A&M University) for providing different types of antibodies, vectors and flies, as well as Dr Levine (University of Toronto) for the signal-processing toolbox to analyse locomotor behaviour
Glycolytic and mitochondrial metabolism are increased in activated HSCs [13, 21, 22]
