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doi: 10.1039/c4mt00230j
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however, treatment with timolol 0.5% had no benefit, despite identical IOP reduction effects [61]
Wild type SOD1 can be misfolded by the aberrant translation, post-translational modification or oxidative modifications, due to the pathological conditions of the CNS environment, and produce toxic insoluble aggregates, as mutated SOD1 (Bosco et al., 2010
