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These individuals are usually completely dependent on others for care, require tube feeding, are unable to complete personal hygiene, and are highly sensitive to sensory stimuli (11)

Furthermore, an animal study showed the protective effect of CoQ10 against RIF+INH-induced hepatotoxicity (16)

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The key to treatment of mental health disorders such as depression and anxiety is to initiate patients on the lowest doses possible and titrate upward every 2 weeks depending on underlying liver disease severity, patient tolerance, and emergence of adverse events