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T-5224, a specific inhibitor of AP-1, was found to be effective in ameliorating doxorubicin-induced myocardial injury [147]
A collateral problem is that L-DOPA's duration of action decreases, because as the population of dopaminergic neurons decreases, it is no more effectively taken up by the neurons, transformed in dopamine, and gradually released
Nutrition Reviews , 48(8), 297-309
Biol Chem 401: 793809, 2020