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Finally, the TS2/16 scFv was purified on size-exclusion chromatography with Superdex 75 Increase 10/300 GL column (Cytivia) on the KTA pure chromatography system (Cytivia) in 1 HBS running buffer (20 mM HEPES pH 7.3, 300 mM NaCl)
The primary nutrients are folate (vitamin B9) and vitamin B12
Schwaller, J
Additional TME factors, including IL-6 and PD-1AhR signaling, exacerbate mtROS accumulation and promote metabolic exhaustion, ultimately leading to NK cell apoptosis and loss of intrahepatic tumor surveillance [11, 172]
