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Description
'ecstasy') produces a neuro-inflammatory response in rats characterized by an increase in microglial activation and IL-1beta levels

These findings were further supported by a study from the United States that also confirmed increases in serum transaminases and histopathologic scores when administered the green tea extract after APAP (Lu et al., 2013)

Key mechanisms include the regulation of the DIO2-MAPK/ERK-mTOR and SHH signaling pathways

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