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Such conditions as sub-tropical temperatures and the influence of mangrove swamps and freshwater run-off from dense vegetation have been identified in parts of New Zealand

DOI: 10.4161/psb.6.6.15147 6

However, facing pathological stimuli such as protein aggregates, microglia are activated and adopt a pro-inflammatory phenotype, leading to the release of cytokines involving interleukin-1 (IL-1), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-) to exacerbate neuronal impairment (Peruzzotti-Jametti et al., 2024

Some patients may need a manometry test, which involves passing a thin, flexible tube through the nose, down the esophagus, and into the stomach to monitor pressure levels