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Non-mitochondrial ROS sources in diabetes Regardless of whether excessive ROS formation is the primary initiator or accompanying factor in the pathogenesis of diabetes mellitus, oxidative stress plays a key role in the organ complications such as cardiovascular problems, neurological problems (stroke), diabetic retinopathy, nephropathy, and neuropathy
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Methionine and the glutathione pathway Methionine serves as a precursor for cysteine and, subsequently, for glutathione, one of the most important intracellular antioxidants
