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PMID: 28965757
MS-based techniques involve sample preprocessing and the liquid chromatography analysis of proteins and their modifications, making them the preferred method for biomarker discovery (Wei and Li, 2009)

Betaine supplementation may increase insulin- like growth factor (IGF-1) production as a result of stimulation of growth hormone secretion, leading to increased protein synthesis 53,54

Relation of serum insulin-like growth factor-I (IGF-I) and IGF binding protein-3 to risk of prostate cancer (United States) Cancer Causes Control
