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The activation of glial cells was observed in similar regions to those where neuronal loss and atrophy were severe, i.e
250,276 How the changes of H3K27me3 in the ageing process affect the function of stem cells in muscle and blood remain unanswered, yet this inhibitory marker may limit the regeneration potential of these stem cells, which will decrease with age
Examining the adaptive processes that are established to respond to the initial CS burden may help to understand what pathways become defective or are compromised and may contribute to the pathogenesis of COPD