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The biochemical phenotype is indistinguishable from NAGS deficiency

In the lean group, only plasma IL-18 showed a significant negative correlation with MOTS-c levels, but no significant relationships with insulin resistance markers (HOMA-IR, insulin) or lipid metabolism indicators (Supplementary Table 46)

By improving fat transport into the mitochondria, L-Carnitine allows for more efficient use of stored fat, potentially supporting greater energy output and improved workout performance
