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A second reason is that fluoride is a relatively poor leaving group (the topic of Section 6.4)

Sentman ML, Brannstrom T, Westerlund S, Laukkanen MO, Yla-Herttuala S, Basu S, Marklund SL

Tobacco: A favorite for low-carbon biorefinery

Blood 80(10):2604-9, 1992
