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A low level of methylation was detected in all three CpG islands in the hepatitis samples (6.6%, 6% and 17.5% in CG1, CG2 and CG3, respectively), whereas, the HBV DNA detected in cirrhosis tissue was mostly unmethylated in CG1 (0%) and CG2 (0.8%) and a low level of methylation was found in CG3 (10.8%)

Rather than being derived from pharmaceutical companies or synthesized purely for experimental purposes, it was modeled on a protective compound that the human body produces naturally

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[DOI] [PMC free article] [PubMed] [Google Scholar] 172.Kamphorst BE, Stoll D, Gressner AM, Weiskirchen R