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Other papers were discovered by hand-searching the references of reviews of disease-modifying therapies in progressive multiple sclerosis

Front Immunol 13 (2022)

If the ability to reduce GSSG to GSH is overwhelmed by a high burden of oxidative stress, GSSG can be exported out of cells or react with protein sulphydryl groups to prevent a major shift in the redox equilibrium [11], thereby depleting cellular GSH

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