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Future research should focus on a deeper understanding of the molecular and cellular mechanisms underlying melittins antiarthritic activity
J Nutr 130 : 26532657

Despite initial pharmaceutical interest, AOD 9604 did not progress through the full clinical trial pathway required for regulatory approval, and it holds no Marketing Authorisation (MA) from the MHRA or EMA

Specifically in vehicle-treated rats, POI caused a significant slowing of small intestinal transit as assessed as demonstrated by a decrease in the geometric center (Figure 1B) and a decrease in the distance traveled along the small intestine by the head of the meal compared to nonsurgery controls (Figure 1C)
