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Some studies have shown that taking L-carnitine reduces the production of lactic acid and therefore delays the moment of fatigue

However, other studies including a more detailed investigation revealed that OPT2 is primarily localized to golgi and partly to the plasma membrane and have demonstrated that the opt2 has a severe vacuolar morphology (Yamauchi et al., 2015)

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40 Other studies have confirmed the efficacy of 7T MRS for in vivo detection of 2-HG in brain tumors, with discrimination of this metabolite from glutamine, glutamate and GABA