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While losing some lean mass during aggressive weight loss is expected, this ratio is favorable compared to diet-only approaches where lean mass losses can reach 30-40%
This product also promotes the conversion of methylmalonic acid to succinic acid and participates in the tricarboxylic acid cycle
These cells have a defect in OXPHOS and rely on oxidative glutamine-glutamate-alpha-ketoglutarate metabolism for survival (Figure 2)
