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Calcif Tissue Int 72:3241

M.WuX.et al (2020)

5.1 Relationship between migraine and oxidative stress 5.1.1 Clinical evidence of oxidative stress 5.1.1.1 Antioxidant capacity In contrast to the control group, patients with migraine without aura had higher total oxidative status (TOS), higher oxidative stress index (OSI), and lower total antioxidant status (TAS) (Tripathi et al., 2018)

A further small study done recently on 10 paediatric patients similarly found that intranasal OH-Cbl normalised serum B12 levels in deficient patients ( Subcutaneous B12 Subcutaneous B12 is occasionally used, especially in patients with inborn errors of cobalamin metabolism, who need high pharmacological doses of B12 to maintain their B12-dependent metabolic pathways and related biochemistry within normal range