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This balance is crucial for cellular homeostasis, as evidenced by studies in various cancer forms where somatic mutations of HATs or altered HDAC activity due to chromosomal translocation can lead to oncogenic orientations

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J Neurochem 87:127135 Segawa H, Fukasawa Y, Miyamoto K, Takeda E, Endou H, Kanai Y (1999) Identification and functional characterization of a Na+-independent neutral amino acid transporter with broad substrate selectivity
