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J Clin Endocrinol Metab (2020) 105:e45517
It is important to highlight that numerous studies in small groups of patients with kidney disease have demonstrated significant improvements in GFR following recombinant IGF-1 administration
doi: 10.1093/schbul/sby051
Then, ATP depletion leads to the failure of energy-dependent ion pumps (e.g., Na + /K + -ATPase), resulting in ionic imbalances, including the influx of calcium (Ca 2+ ), sodium (Na + ), and chloride (Cl ) ions into the cell, and the efflux of potassium (K + ) [23]
